PROPOR HC Filter

ESI Ultrapure/Products/Filters/Parker PROPOR HC Filter
ESI Ultrapure/Products/Filters/Parker PROPOR HC Filter

Product

Parker PROPOR HC Filter

PROPOR HC: High-Performance 0.2 Micron Filter for Sterile Processing

Designed for demanding pharmaceutical and biologic applications, PROPOR® HC filters deliver extended throughput, high flow rates, and reliable performance — even with complex or viscous solutions.

Featuring an optimised, highly asymmetric PES membrane, PROPOR® HC filters act as both a prefilter and a sterilising-grade filter in one, significantly reducing the risk of premature blockage and extending filter life. The low-binding membrane minimises product loss by reducing protein and preservative adsorption, while maintaining low extractables and broad chemical compatibility for critical processes.

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Single Use Assembly Benefits

  • Superior Throughput and Capacity: The optimised membrane configuration with a high-capacity prefilter layer extends filter life and minimises premature blockage, ensuring efficient processing of complex solutions.
  • Validated Sterility: Fully validated by bacterial challenge testing, the PROPOR HC guarantees sterile filtration, meeting the highest standards for product safety.
  • Broad Chemical Compatibility: The PES (Polyethersulfone) membrane construction offers excellent chemical resistance across a wide pH range, making it suitable for diverse applications.
  • Minimal Protein Binding: The low protein-binding PES membrane minimises product loss due to adsorption, ensuring optimal yield.
  • Integrity Testable: The filter allows integrity testing for sterility assurance, providing peace of mind during critical processes.
  • Single-Use Convenience: Available in single-use capsules, the PROPOR HC simplifies filter changeout and reduces validation requirements.
  • Gamma Irradiation and Autoclave Compatibility: The capsules can be gamma-irradiated or autoclaved for terminal sterilisation, ensuring aseptic processing.

Single Use Assembly Technical Data

Brand: Parker

Industry: Pharmaceuticals

Application: Sterile Liquid Filtration and Bioburden Reduction

Product Type: Liquid Filter Element

Materials of Construction

  • Filtration Membrane: Polyethersulfone (PES)
  • Prefilter Membrane: Polyethersulfone (PES)
  • Support Layers: Polyester (upstream and downstream)

Filter Cartridges

  • Inner Support Core: Polypropylene
  • Outer Protection Cage: Polypropylene
  • End Caps: Nylon
  • End Cap Insert: 316L Stainless Steel

MURUS Capsules

  • Core, Sleeve, and Body: Polypropylene
  • End Cap Insert: 316L Stainless Steel
  • Vent Seals: Silicone

DEMICAP Capsules

  • Core and Sleeve: Polypropylene
  • Capsule Body: Nylon
  • End Caps: Nylon
  • Vent Seals: Silicone
  • Filling Bell: Polycarbonate

Syringe Filters

  • Body: Polypropylene

Operating Conditions

Filter Cartridges

  • Continuous: 70 °C (158 °F)
  • Short-term CIP conditions:
    • 20 °C (68 °F) @ 5.0 barg (72.5 psig)
    • 40 °C (104 °F) @ 4.0 barg (58.0 psig)
    • 60 °C (140 °F) @ 3.0 barg (43.5 psig)
    • 80 °C (176 °F) @ 2.0 barg (29.0 psig)
    • 90 °C (194 °F) @ 1.7 barg (24.6 psig)

MURUS Capsules

  • Up to 25 °C (77 °F) @ 5.5 barg (79.7 psig)
  • Up to 60 °C (140 °F) @ 2.8 barg (40.6 psig)

DEMICAP Capsules

  • Up to 40 °C (104 °F)

Certifications & Compliance

  • Fully validated to ASTM F838-05 liquid bacterial challenge
  • Complies with FDA 21 CFR Part 177
  • USP Plastics Class VI – 121 °C compliant

Product Specifications

  • Length Options: 2.5 to 40 inches (65 to 1000 mm)
  • Micron Rating: 0.2 micron

End Cap Configurations

Cartridges:
  • BF / 226 Bayonet
  • Fin / 222
  • Flat Top / 222
  • Recess / 222
  • BF / 222 Bayonet
Demi Cartridges:
  • TRUSEAL
  • 116
  • Demi Stub
  • Demi A & B Std

Inlet & Outlet Connection Sizes

MURUS Capsules:
  • 3/4″ Tri-Clamp
  • 1″ Tri-Clamp
  • 1-1/2″ Tri-Clamp
  • 1″ Hosebarb
  • 1/2″ Hosebarb
DEMICAP Capsules:
  • 1″ Tri-Clamp
  • 1/2″ NPT Male
  • 1/2″ Hosebarb
  • Stepped Hosebarb
  • 1/4″ NPT Male
  • Walther QC
  • Grommel / QC

Additional Options

  • Grades Available: Non-sterile or Gamma-irradiated (MURUS and DEMICAP Capsules)
  • Configurations: In-Line or T-Port (MURUS Capsules)
  • Seal Materials: Silicone, EPDM, Viton

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