Pumps & Control Systems

Category: Pumps & Control Systems

Single-use pumps are equipped with a product-wetted plastic pump chamber that can be replaced as a complete unit for disposal. Single-Use pumps are most commonly used in Biopharma applications where its disposable design feature creates a quicker production process while saving time and money because it eliminates the need for complex sterilization and cleaning validation. Single-use pumps also deliver the required levels of product purity and sterility these applications demand, eliminating the chance of harming the product and decreasing the odds of costly cross-batch or cross-product contamination. In addition, single-use pumps reduce downtime between two batches and are quick and easy to change.

What Are the Benefits of Using a Single-Use Pump?

Low Shear Pump

The Quattroflow pump is a quaternary (4-piston) diaphragm low shear pump that enables gentle pumping through soft “heartbeats”. Each stroke of the four diaphragms is generated by an eccentric shaft, which is connected to the electric motor. This method of operation allows the Quattroflow pump to gently, safely and securely convey shear-sensitive aqueous solutions and biologic products with minimal impact. Single Use Pumps - Low Shear Pumps with pump controller

The four-piston design of Quattroflow pumps also does not require a mechanical seal or wetted rotating parts, ensuring total product containment without abrasion and minimum particle generation. Additionally, the four-piston pumping principle provides risk-free dry running, low pulsation, self-priming and a high turndown ratio. 

No Heat Generation

Compared to Single Use centrifugal pumps, the Quattroflow pump does not generate any heat. Heat generation can largely impact cell viability in critical processes. The gentle operations of the Quattroflow pump is ideally suited for these sensitive applications. 

Low Particle Generation

Unlike the operation of a peristaltic pump, the gentle working principle of Quattroflow pumps has been specifically designed to help eliminate particle contamination of your product. This makes Quattroflow pumps ideally suited for optimizing the handling of expensive and/or sensitive liquids often found in a variety of biopharma applications. Quattroflow QF2500SU Single use pump

Most Common Applications for Quattroflow Single Use Pumps

  • TFF (Tangential flow filtration) 
  • Media Transfer 
  • Purification 
  • Sterile Filtration 
  • Mixing 

If you are looking to replace permanent process pumps with single use pumps, reduce development costs, increase flexibility, and eliminate cleaning and validation requirements, ESI Ultrapure has the solution for you.


Get in touch with our dedicated team. We are here to help!