Enhance bioprocessing safety and efficiency with Aramus™ 2D Bag Assemblies

Protect your high-value fluids with Aramus™ 2D bag assemblies and reduce the risk of product loss, contamination, or compromised quality.

Bioprocess Bags - 2d bag assembly

The Aramus Single-Use 2D Bag Assembly is a meticulously designed pre-assembled system explicitly tailored for bioprocessing. It comprises a pre-sterilised 2D bag, tubing, and connectors. The bag itself is crafted from various materials, ensuring compatibility with diverse bioprocessing applications, and enhancing its versatility and effectiveness.

Are you concerned with Single-Use Materials affecting Cell Growth?

All additives, either by-products or purposely added chemicals like antioxidants, UV stabilizers, or processing agents—are potential leachables. These leachables can have a negative effect on processes and products and have also been shown to negatively affect cell growth. The Aramus bag is made of a single-layer fluoropolymer film with no additives that can leach into your process. The Aramus bag assembly brings a new level of assurance to your process

Are you concerned with particulates coming from single-use bag films?

One of the standout advantages of the Aramus Single-Use 2D Bag Assembly is its exceptional ability to minimize the risk of contamination. Particles both internal and external to bag films are a potential contamination risk to your bio-manufacturing process. Aramus single-use bag assemblies are manufactured in an ISO Class 5 environment, greatly reducing the potential for particulate contamination. The advantage of manufacturing in an ISO Class 5 environment is it has fewer foreign particles from both the manufacturing environment and the manufacturing process itself.

Do you have temperature limitations with single-use materials?

Most single-use bag assemblies on the market are limited to a temperature range of 20 to 40 °C. This is due mainly to the bag film itself. Below -40°C, the material becomes brittle and fails. Rapid changes in temperature or temperatures below -70 °C can cause delamination of the film layers and film failure due to cracking. The Aramus Single-Use 2D Bag Assembly is designed and tested from -85° to 40 °C. However, the film and bag boat fitment is made from a single layer of fluoropolymer material that is suitable for use down to -200 °C and as high as 200 °C. Please have a look at this short video showing the cold temperature performance test of the Aramus film compared to two other materials used for single-use bags. Each material is placed in liquid nitrogen at -196°C for 30 seconds.

Suitable Applications

2D Bag Assemblies for bioprocessing - Aramus


The Aramus Single-Use 2D Bag Assembly finds suitability across an extensive range of bioprocessing applications:

  • Downstream bioprocessing
  • Storage (frozen or room temp)
  • Sampling
  • Stem cell freezing
  • Critical media storage
  • Applications where compatibility is of concern.
  • Final fill.

For more information on single-use bag assemblies, please contact ESI Ultrapure in Ireland at +353 21 4510900, UK at +44 1633 877505. They will be happy to answer your questions and discuss your requirements.


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