Parker PureTec® Automated Tangential Flow Filtration System

Benefits

Complete Development System

Designed for process development, the PureTec® provides a comprehensive solution for concentration and diafiltration workflows in a single, automated platform.

Real-Time Data & Optimisation

Continuously collects and displays real-time filtration data, enabling quick adjustments and performance optimisation using built-in tools.

Scalable Parameters for Easy Tech Transfer

Parameters are fully scalable, ensuring a smooth transition from development to pilot or production-scale systems.

Flow and Automated Pressure Control

Precisely maintains flow rates and transmembrane pressure (TMP), allowing consistent performance in both constant rate and constant pressure modes.

Safe, Walk-Away Operation

Automation and alarm-based safety features allow for hands-free processing and reduced manual oversight.

Intuitive User Interface

A user-friendly application interface simplifies setup, operation, and monitoring—even for complex protocols.

Application Benefits

Concentration

Flexible Control: Operates in either constant rate or constant pressure mode, with adjustable parameters that can be changed without stopping the pump.
Optimisation:
- In constant rate mode, stepwise increases in feed rate alongside permeate monitoring help determine the optimal feed rate for maximum yield.
- In constant pressure mode, stepwise increases in TMP help identify the pressure that delivers the highest permeate flow.

Diafiltration

Electrolyte Removal: Efficiently removes salts and other undesired solutes by replacing permeate with fresh exchange buffer through a selected TFF membrane.
Constant Volume Control: In constant volume diafiltration, the system automatically replaces removed permeate with an equal volume of exchange buffer, typically requiring ~10 volume exchanges.
Small Volume Solution – Suction-Based Diafiltration: A SciLog® pressure vessel feeds buffer into the retentate vessel, maintaining a closed system until programmable end points are reached.
Large Volume Solution – ChemTec® Integration: For higher volumes, the ChemTec® system uses a balance to monitor and replenish fluid levels in the retentate vessel, maintaining buffer exchange until a target volume is reached.

Technical Data

Description
Dimension / Weight	Width: 5.75″ (146 mm) x Height: 8.5″ (2126 mm) x Depth: 11″ (279mm): 14 lbs (6.4 Kg)
Enclosure & Rating	16 Ga, aluminium baked epoxy blue 4-40dC, 0-100% humidity, IP20
Pressure Sensors	Accommodates up to three disposable pressure sensors. The calibrated pressure range is 0-60 psi. Any point within this range can be recalibrated using an external pressure reference source.
Power	115 / 220-240 VAC, 60/50 Hz, 75 Watts, double-fused: T1AL 250V (CE: IR35A 250VAC)
Motor / Encoder	8, 160, 600 RPM, 30 VDC, 3.8A, 120 ppr 8 and 160 RPM, 100 ppr 600 RPM
I/O Ports	Male DB9 scale connections (RS-232), female DB9 printer or PC Connection (RS-232), external ISO DB37 connector, 1 TTL input, 4 TTL output, 3 4-20mA. Analogue Input: Constant rate / constant pressure filtration with user-definable alarms.
Operational Mode	Constant pump rate, constant inlet or transmembrane pressure (TMP)