ESI Ultrapure/Products/Filters/Parker PROPOR SG Filters

ESI Ultrapure/Products/Filters/Parker PROPOR SG Filters

Product

Parker PROPOR SG Filters

PROPOR SG filters offer fast, economical, and validated sterile filtration for pharmaceutical liquids, including biopharmaceutical products, intermediates, buffers, water, and reagents. Featuring an asymmetric pore structure and high void volume, PROPOR SG membranes deliver high throughput and exceptional flow rates, outperforming competitive PES and alternative membranes. Their low protein and preservative binding properties minimise product loss due to adsorption. Designed for pharmaceutical processing, PROPOR SG filters are characterised by low extractable levels and broad chemical compatibility across the full pH range, including organic solvents.

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Single Use Assembly Benefits

Up to 3.5 times higher flow rates compared to competitive sterilising-grade filters
Fully validated and integrity testable membrane, ensuring sterility assurance
Low binding properties minimise product loss
MURUS and DEMICAP capsules can be gamma-irradiated and autoclaved
PFAS-free options are available for safer filtration

Single Use Assembly Technical Data

Brand: Parker

Industry: Pharmaceuticals

Application: Sterile Liquid Filtration and Bioburden Reduction

Product Type: Liquid Filter Element

MATERIALS OF CONSTRUCTION

Filtration Membrane: Polyethersulphone
Upstream & Downstream Support: Polyester

FILTER CARTRIDGES

Inner Support Core & Outer Protection Cage: Polypropylene
End Caps: Nylon
End Caps Insert: 316L Stainless Steel

MURUS DISPOSABLE FILTER CAPSULES

Core, Sleeve & Capsule Body: Polypropylene
End Caps Insert: 316L Stainless Steel
Standard O-Rings/Gaskets & Capsules Vent Seals: Silicone

DEMICAP FILTER CAPSULES

Core & Sleeve: Polypropylene
End Caps & Capsule Body: Nylon
Capsules Vent Seals: Silicone
Filling Bell: Polycarbonate

SYRINGE FILTERS

Body: Polypropylene

RECOMMENDED OPERATING CONDITIONS

FILTER CARTRIDGES

Up to 70 °C (158 °F) continuous operating temperature and higher short-term temperatures during CIP to the following limits:

Temperature		Max. Forward dP
°C	°F	(BAR)	(PSI)
20	68	5.0	72.5
40	104	4.0	58.0
60	140	3.0	43.5
80	176	2.0	29.0
90	194	1.7	24.6

MURUS DISPOSABLE FILTER CAPSULES

Up to 25 °C ( 77 °F) @ 5.5 barg (79.7 psig)
Up to 60 °C (140 °F) @ 2.8 barg (40.6 psig)

EFFECTIVE FILTRATION AREA (EFA)

10″ (250 mm)	0.55 m² (5.92 ft²)
K Size	0.26 m² (2.79 ft²)
A Size	0.20 m² (2.15 ft²)
B Size	0.10 m² (1.07 ft²)
E Size	0.05 m² (0.53 ft²)
Syringe ø50 mm	14.50 cm² (2.25 in²)

STERILISATION

	Autoclave		Steam-in-Place
	Cycles	Temp	Cycles (30 min.)	Temp
Cartridges	10	130°C (266 °F)	30	130°C (266 °F)
MURUS	5	130°C (266 °F)	–	–
DEMICAP	10	130°C (266 °F)	–	–
Syringe	1	130°C (266 °F)	–	–

PROPOR SG filter cartridges can be sanitised with hot water at up to 90 °C (194 °F) and are compatible with a wide range of chemicals.

BIOLOGICAL SAFETY

Materials conform to the relevant requirements of 21CFR Part 177 and current USP Plastics Class VI – 121 °C and ISO10993 equivalents.

QUALITY STANDARDS

Pharmaceutical grade products are manufactured by cGMP, 100% flushed with pharmaceutical grade purified water and integrity tested before despatch. A sample of each lot is tested to demonstrate conformity to validated claims.

GAMMA-IRRADIATION

PROPOR SG MURUS & DEMICAP disposable filters can be gamma-irradiated up to a maximum dosage of 40 kGy.

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