Cleanline™ Connector

Are you looking to maximise efficiencies in single-use bioprocessing applications?

Single-use bioprocessing efficiency is the rate of fluid transfer from one stage of the process chain to another which is often limited to the use of ¾” to 1” hoses.

Why is this? It is largely because there has not yet been a reliable way to connect hoses larger than 1” in diameter.

ESI Technologies is now the proud distributor for Refine Technology, a manufacturer of the CleanLine™ 1.5” Single Use Connector. The CleanLine™ connector promises increased efficiencies in large-scale sterile fluids management across media preparation, filtration, bioreactor harvesting, chromatography, concentration / diafiltration, and bulk formulation operations.

Single Use Connector

Cleanline™ Connector Benefits


  • Strong, robust 1½” connection for high pressure and flow rates.
  • Dual seals minimize contamination risk from the inside and outside.
  • Genderless connecting: less inventory, less complexity, more flexibility.
  • Connection secured with industrial strength bolts.
  • More cost-effective; less downtime.
  • Hose and custom assemblies are available.
  • Easy to assemble.


  • Connector body material meets USP Class VI, 21 CFR 177.1655, and is Animal Derived Component Free. The material of construction is Polysulphone.
  • 100% Lot traceable.
  • Cleaned, assembled and packaged in an ISO 7 Clean Room.
  • Gamma and autoclave stable.
  • Operating temperature: 4 – 50°C.
  • Operating pressure: 26” Hg up to 5.5 bar (80 PSIG).


  • Upstream to downstream transfer.
  • Media buffer preparation and transfer.
  • Bioreactor harvest.
  • Sterile waste removal from the process stream.
  • WFI or sterile water transfers.
  • Sterile bulk formulation downloads.

For more information, please send us an enquiry or call us on Ireland: +353 21 4510900, UK: +44 1633877505 or Benelux: +31 85 0499770.  We look forward to hearing from you.


Get in touch with our dedicated team. We are here to help!